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بایگانی/آرشیو برچسب ها : antagonist

Irilone as a progesterone receptor (PR) effect supporter in endometrial and ovarian cancer cell lines

Dr. Mehdi Nabati Iranian Drug Designer

Irilone as a progesterone receptor (PR) effect supporter in endometrial and ovarian cancer cell lines   Estrogen and Progesterone receptors (ER, PR) are ligand-induced transcription factor members of the steroid hormone receptor (SR) subfamily of nuclear receptors. Those receptors and their corresponding steroid hormones (estradiol and progesterone) play their roles …

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zotepine as an atypical antipsychotic antagonist

Physicochemical properties analysis and dopamine D2 receptor (D2R) docking of zotepine as an atypical antipsychotic antagonist

Zotepine as an atypical antipsychotic antagonist Schizophrenia is a chronic, critical condition characterized by collective psychotic signs and symptoms, exhibited as alterations in patient’s thoughts, perception and behavioral attributes. Schizophrenia is mostly accompanied by symptoms that are generally categorized into two major groups: 1: Positive symptoms including hallucinations (auditory, visual, …

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۱۱C-LY2795050 as a novel antagonist tracer for PET scan of the kappa (κ) and mu (µ) opioid receptors

Dr. Mehdi Nabati Professor of Organic Chemistry

۱۱C-LY2795050 Radiopharmaceutical A receptor into the cells has two main operations when it makes complex with an agonist compound and or an antagonist molecule. The agonist-receptor complex formation causes the receptor activation, but the binding of antagonist molecule to the receptor causes its blocking. In pharmacology, the antagonist compounds have …

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