Tag Archives: drug design

Substitution of carbonyl group of ellagic acid with silanediol group for better inhibition of VEGFR-2 Kinase enzyme What is cancer? The major cause of death worldwide is cancer. Surgery, chemotherapeutic agents and radiation which are cancer therapy have not been much efficient in the reduction of cancer occurrence and raising …

Withaferin A (WIT) interaction with β–Tubulin Withaferin A (WIT) Withaferin A (WIT) is an important natural compound extracted from the Indian medicinal plant Withania somnifera. This plant has been used for over 3000 years in Unani Indian medical system. Also, its extracted medicinal compound has been in ayurvedic medicine and …

Design of novel tazarotene derivatives as potential antipsoriatic drugs   What is Psoriasis? Psoriasis is a prevalent chronic inflammatory skin condition afflicting about 2-4% of patients all over the world. Psoriasis is mostly characterized by the skin covered with red, well-defined, hardened plaques with silver and micaceous scale. Complications associated …

The molecular structure and the stability parameters of 99mTc-MDP Medronate, commonly known as methylene diphosphonate or MDP, is the smallest bisphosphonates, recognized as a family of drugs used in treatment of various bone diseases. Bisphosphonates are the structural analogs of native pyrophosphate with a P-C-P backbone instead of P-O-P. The …

FPTT for PET scan of breast cancer Breast cancer is a complicated, heterogeneous disease, mostly accompanied by symptoms such as a mass in the breast, changes in breast shape, size and color, pain in breast or nipple, fluid discharge from the nipple, inverted nipple, dimpling or irritation of the skin. …

Novel drugs for autism treatment Autism spectrum disorders (ASDs) are complex and prevalent neurodevelopmental disorders predominantly diagnosed through observation of a wide variety of atypical behavior, expressed by impairments in socialization, communication, thinking, interests, activities and cognitive skills as well as restricted and repetitive behavior. Autism is considered a heterogeneous …

Curriculum vitae *************************************** Mehdi Nabati Ph.D. of Organic Chemistry Date of Birth: 22/04/1988 Place of Birth: Maragheh, East Azarbaijan, Iran Marital Status: Single Mobile Number: +989011828140 E-mail: mnabati@ymail.com *************************************** EDUCATION AND RESEARCH Azarbaijan Shahid Madani University, Tabriz, Iran . Ph.D., Organic Chemistry, with Dr. Mehrdad Mahkam, Sept. 2012 – ۲۰۱۵ …

به طور معمول در یک آزمایشگاه تحقیقاتی شیمی یا مواد، محققین با مقادیری به اندازه صدم تا هزارم مول سروکار دارند. اگر حتی فرض کنیم تجهیزاتی در آزمایشگاههای معمول شیمی داشته باشیم که قادر باشد در گستره نانومول نیز واکنش را ردیابی کند، باز تعداد مولکولهای موجود در واکنش بسیار …